Built by a practicing OMFS resident

When a patient is sedated,
there's no room for uncertainty.

SedationRef puts verified, weight-based dosing and emergency protocols at your fingertips — so the right answer is never a mental calculation away from a bad outcome.

Built by an OMFS resident at a Level I trauma center. Sourced from FDA labels, AAOMS OAE Manual 10th ed, AAOMS ParCare 2024, AHA ACLS/PALS 2025, ASRA, MHAUS, and StatPearls.
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Free during early access  ·  No spam  ·  Installs as a PWA — works offline after first load

FDA · AAOMS OAE 10th ed · ASA · AHA
ACLS 2025 · PALS 2025 · ASRA · MHAUS
Show-work dose transparency
Offline — no wifi or cell needed
Finally a reference that thinks the way I do mid-case — bolus, titrate, ceiling, all in one view. I don't reach for anything else.
Beta User
OMFS Resident, Academic Medical Center
5
IV sedation drugs — fully sourced to FDA label and current guidelines
The show-work calculations are what sold me. I can hand this to a resident and they understand exactly where every number comes from.
Beta User
Attending OMFS, Private Practice

The tools most providers use weren't built for this moment.

In-office sedation is high-stakes and fast. When something starts going wrong, you don't have time to reconstruct an answer from memory or a general-purpose drug app.

You're doing mental math while managing a sedated patient

Weight-based dosing requires calculation. Every second spent computing is a second not spent watching the patient.

⚠ A dosing error under sedation is rarely recoverable in the office.

Generic drug apps weren't built for this setting

Wrong stock concentrations, missing elderly ceilings, no high-risk adjustments. Off-the-shelf tools introduce the gaps they claim to close.

⚠ Trusting the wrong reference is worse than having none.

When an emergency hits, memory fails

Laryngospasm, anaphylaxis, LAST — adrenaline degrades recall. You need a structured protocol, not a mental checklist built under stress.

⚠ The cases that go wrong are the ones nobody expected.

Because the cases you prepare for
are the ones you survive.

Every critical in-office emergency — structured, weight-adjusted, one tap away. Not buried in a textbook.

Critical

Laryngospasm

Step-by-step from recognition to succinylcholine dosing — with your patient's weight pre-calculated.

Critical

Anaphylaxis

Epinephrine dose, route, timing, and biphasic reaction warning — sourced to AAOMS and AHA.

Critical

LAST & Intralipid

Local anesthetic systemic toxicity protocol with Intralipid dosing and ASRA hotline built in.

Serious

Respiratory Depression

Airway sequence, reversal agent dosing, re-sedation monitoring — the full picture at once.

14 emergency protocols total — cardiac arrest, MH, bronchospasm, seizure, aspiration, and more. Each one sourced to AHA ACLS 2025, AAOMS ParCare 2024, ASRA, and MHAUS. Weight-adjusted doses update automatically when you enter your patient.

Designed for the procedure room, not the ICU.

Every feature built around what you actually need when a patient is sedated in the chair.

Weight-based dosing

Enter age and weight, get instant mg and mL for every drug — step-by-step calculations shown alongside every value.

High-risk dose adjustments

Elderly (≥60), obese/OSA, ASA III–IV — ceilings automatically reduced. One toggle, every dose recalculates.

Bolus / Titrate / Ceiling

All three values shown simultaneously — mg and mL — exactly how clinicians think during an active case.

Local anesthetic calculator

Carpule limits by agent and patient weight, epinephrine tracking across multiple agents, and LAST risk reminders.

Works offline after first load

Installable PWA. Once you've opened it once on your device, all dosing and protocols are cached — available without wifi or cell signal in the procedure room.

Printable case summary

One page: all calculated doses, reversal agents, and emergency drug weights — in mg or mL mode for the chart.

The answer is already there when you reach for it.

You've just started titrating. You want to know exactly how much mL is in that next increment — and what the ceiling is before you push it.

Scenario — Midazolam · 70 kg adult · Stock 1 mg/mL You opened the card. Bolus was 1–2.5 mg (1–2.5 mL). You're titrating 0.5–1 mg increments. The ceiling is 5 mg — FDA label — and the app tells you exactly when you're approaching it.
No conversion in your head — mg and mL side-by-side
Ceiling source labeled — FDA label vs. clinical rec, never ambiguous
Show calc reveals exact arithmetic — auditable at any time
SedationRef
In-Office Sedation Reference
Adult · 35 yr · 70 kg · BMI 24 · ASA II · Standard Risk
Midazolam (Versed)
Benzodiazepine  ·  Stock: 1 mg/mL
Adult
Initial Bolus
mg / mcg
1–2.5
flat dose
mL / cc
1–2.5
@ 1 mg/mL
Titrate
mg / mcg
0.5–1
q2–3 min
mL / cc
0.5–1
@ 1 mg/mL
Ceiling
mg / mcg
≤5 mg
FDA label
mL / cc
≤5.00 mL
5 mg ÷ 1 mg/mL
▾ show calc
Bolus: flat dose · FDA ceiling 5 mg
Bolus mL: 1 mg ÷ 1 mg/mL = 1.00 mL  |  2.5 mg ÷ 1 mg/mL = 2.50 mL
Titrate mL: 0.5 mg ÷ 1 mg/mL = 0.50 mL  |  1 mg ÷ 1 mg/mL = 1.00 mL
Ceiling mL: 5 mg ÷ 1 mg/mL = 5.00 mL (FDA label)
Clinical note Administer over ≥2 min. Wait ≥2 min before redosing. ASA III–IV or opioid co-admin: start 1 mg, reduce 30–50%. Elderly (age ≥60): ceiling ≤2 mg — clinical rec.
IV Dose
Local Anx
IV Meds
Emergency
E-Drugs
Reversal
Reference

Not just for emergencies — for every sedation you do.

The value isn't only in the emergency protocols. It's in opening SedationRef before every case as part of your pre-sedation routine.

Pre-op — enter the patient
Age, weight, height, ASA class. Every drug card updates instantly. High-risk adjustments apply automatically.
Intra-op — reference at a glance
Bolus, titrate, ceiling — all visible without scrolling. Add the next drug in the sequence without recalculating.
Post-op — print for the chart
One-tap case summary in mg or mL. All calculated doses, reversal agents, and emergency weights on a single page.
SedationReference — Case Summary
◆ mg / mcg Mode · March 27, 2026 · 08:14 AM
J. Martinez
Adult · 42 yr · M · 78 kg · BMI 27 · ASA II
Pre-op: BP 124/76 · HR 68 · SpO₂ 99%
IV Sedation · 78 kg
Midazolam
Initial bolus
1–2.5 mg
flat dose · FDA ceil 5 mg
Titrate: 0.5–1 mg q2–3 min
Ceil: ≤5 mg — FDA
Fentanyl
Initial bolus
78–156 mcg
1–2 mcg/kg × 78 kg
Titrate: 25 mcg q3–5 min
Ceil: ≤150 mcg/hr — clinical rec
Propofol
Induction bolus
39–78 mg
0.5–1 mg/kg × 78 kg
Titrate: 10–20 mg q30–60 sec
Ceil: titrate to effect
Reversal Agents
Flumazenil
Benzo reversal
0.2 mg IV q1 min
max 1 mg total
Naloxone
Opioid reversal
0.4 mg IV q2–3 min
titrate to RR, not consciousness
Emergency Drugs — 78 kg
Epi — Anaphylaxis
0.3–0.5 mg IM ant. thigh
0.5 mg IM
0.01 mg/kg × 78 kg
Succinylcholine
Laryngospasm / RSI
8–23 mg IV
0.1–0.3 mg/kg · RSI: 117 mg
Atropine
Bradycardia
1 mg IV
max 3 mg total
SedationReference · sedationref.com
⚠ Titrate to effect — always individualize. Clinical guide only.
March 27, 2026

Print in mg/mcg or mL/cc mode — doses update based on your stock concentrations.

Every number has a citation.

Dosing is only as good as its source. Every value in SedationRef is traceable to a primary reference.

Drug Dosing
FDA Prescribing Labels
Midazolam (Pfizer 2024), Propofol, Ketamine, Fentanyl, Dexmedetomidine — current label ceiling and dose ranges
Office Anesthesia
AAOMS OAE Manual, 10th ed.
Office Anesthesia Evaluation Manual — required emergency drug kit, monitoring standards, and vasopressor categories
Sedation Guidelines
AAOMS ParCare 2024
Parameters of Care — pre-op evaluation, monitoring requirements, discharge criteria, fasting guidelines
Cardiac Emergencies
AHA ACLS 2025 · AHA/AAP PALS 2025
Adult and pediatric cardiac arrest algorithms, antiarrhythmic dosing, post-ROSC care
LAST / Intralipid
ASRA LAST Checklist 2023
American Society of Regional Anesthesia — Intralipid dosing, seizure management, epinephrine dose limits in LAST
Additional Sources
MHAUS · Malamed 7th ed · StatPearls
Malignant hyperthermia protocols, local anesthetic dosing, clinical reviews — with source noted per drug card

Built for providers who manage their own sedation.

Purpose-built for the in-office sedation environment — not adapted from a hospital anesthesia tool.

Oral & Maxillofacial Surgeons
OMFS Residents
Oral Surgery Groups & DSOs
Dental Anesthesiologists
Anesthesiologists — Office-Based
CRNAs in Office Settings

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Early access is free. Pricing begins at launch.

For clinical reference only. Not a substitute for provider judgment, formal sedation training, or institutional protocols.